Macrocyclic glycopeptide‐based chiral selectors for enantioseparation in sub/supercritical fluid chromatography
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چکیده
منابع مشابه
Enantioseparation in CE using macrocyclic antibiotics as chiral selectors
Enantiomer separation represents an important topic especially in pharmaceutical and environmental fields where many drugs and pesticides are racemic compounds. In some cases, only one of the enantiomers has pharmacological or pesticidal activity while the other may exhibit antagonistic activities, unwanted side effects or even toxic effects. Therefore, the development of new enantioseparation ...
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متن کاملDevelopment of a new method based on chiral ligand-exchange chromatography for the enantioseparation of propranolol
A new chromatographic procedure was proposed for the separation of propranolol (PRN) enantiomers based upon enantioselective chiral ligand-exchange chromatography. The separation was carried out on a short C8 column leading to considerably short separation time. L-alanine and Cu2+ were applied as chiral selector and central bivalent complexing ion, respectively. It was found that the kind of co...
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ژورنال
عنوان ژورنال: Analytical Science Advances
سال: 2020
ISSN: 2628-5452,2628-5452
DOI: 10.1002/ansa.202000099